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Also, in patients with PH, limited liver resection can be performed with results comparable to those in patients without PH. Recently, authors have not detected a significant correlation between PH and liver failure after surgery. The aims of this study are to assess the results of liver resection in patients with HCC and cirrhosis with PH and the relationship in terms of survival between Child-Pugh stage, the extent of hepatic resection and the presence of clinical PH. Influence of the extent of hepatectomy on the portal hypertensive state in patients with hepatoma. The authors show that resection is safe in CTP. Among different Child-Pugh class patients we did not observe statistically significant differences in 3- and 5-year survival between patients with or without PH. Hepatocellular carcinoma HCC is the fifth most common cancer and the third leading cause of cancer death worldwide[ 1 – 3 ].

Survival analysis in patients with Child-Pugh A and B cirrhosis did not demonstrate significant differences in patients with or without PH. Portal hypertension PH is related to increase in intrahepatic resistance due to the structural subversion of the cirrhotic liver and loss of vascular bed, and bleeding from gastro-esophageal varices is one of the most important complications of cirrhosis. Conversely, surgical resection of 2 or more segments in patients with PH results in significantly shorter survival and should not be recommended. Surgical treatment is the most effective treatment for HCC and the mortality after surgery has decreased in recent years in relation to improved surgical techniques and peri-operative management of patients. The authors justified these results because liver resection in patients with PH can reduce the portal vascular bed without a reduction of portal flow and this condition can lead to a further increase of portal pressure. Short- and long-term outcomes after hepatic resection for hepatocellular carcinoma with concomitant esophageal varices in patients with cirrhosis. The authors show that resection is safe in CTP. Surgery can result in good long term survival in patients with PH submitted to limited resection; conversely, PH had strong adverse prognostic significance in patients who underwent resection of two or more segments.

Survival analysis in patients with Child-Pugh A and B cirrhosis did not demonstrate significant differences in patients with or without PH. The one and 3-mo mortality rates were 4. Moreover, limited resections wedge or one segment showed no statistical differences between patients with or without PH.

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In this retrospective study, the authors compare the results of liver resection for HCC in patients with and without PH. More recently, Choi et al[ 34 ] reported that the 5-year survival rate of patients with morola PH affected by single nodular HCC without macrovascular invasion was Univariate analysis for survival was performed with the Kaplan Meier method, with the Log Rank test to verify significance of differences.

The 3-year and 5-year survival in patients without PH was higher than in patients with PH Best Pract Res Clin Gastroenterol. Liver resection is currently the treatment of choice for single HCC and it is a safe treatment mltola terms of peri-operative complications, even in patients with liver cirrhosis[ 6simonr ].

Management of hepatocellular carcinoma. HPB Oxford ; 7: On the contrary, other authors have not detected a significant correlation between PH and liver failure after sione. Also, in Child-Pugh class A patients the survival analysis did not show significant differences in patients with or without PH, with a 3-year and 5-year survival of This is a retrospective analysis from a single jotola.

The prevalence of PH in all patients was Applications This study confirms that the presence of PH at the time of surgery is not an absolute contraindication to resection in patients with liver cirrhosis.

These authors studied 77 patients divided into 3 groups based on the presence or absence of PH and bilirubin level. Support Center Support Center.

A retrospective analysis of patients with HCC on a background of cirrhosis was submitted to curative liver resection. Patients with PH at the time of surgery showed worse liver function and this justifies the increased number of complications related to the deterioration of liver function and the increased postoperative 3-mo mortality.

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Predictors of large ssrie varices in patients with cirrhosis. Overall survival analysis in patients. Survival analysis in patients with Child-Pugh B cirrhosis did not demonstrate significant differences in patients with or without PH 3-year survival of Neither multiple tumors nor portal hypertension are surgical contraindications for hepatocellular carcinoma. Factors associated with early recurrence after resection for hepatocellular carcinoma and outcomes.

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Improvement in perioperative outcome after hepatic resection: When resection of two or more segments was performed, survival was significantly longer in patients without PH with a 5-year survival of The Brisbane terminology of liver anatomy and resections. A prospective analysis of our approach.

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Recently, authors have not detected a significant correlation between PH and liver failure after surgery. The mean follow-up after surgery was Improved long-term survival after liver resection for hepatocellular carcinoma in the modern era: Recurrence after liver resection for hepatocellular carcinoma: Is liver resection justified in advanced hepatocellular carcinoma?

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A patients regardless of PH, in patients undergoing limited resection. Although the rate of postoperative complications in patients with PH is greater, the results in terms of survival in the group of Child-Pugh class A patients is similar in patients without PH.

Conversely, surgical resection of 2 or more segments in patients with PH results in significantly shorter survival and should not be recommended. The aims of this study are to assess the results of liver resection in patients with HCC and cirrhosis with PH and the relationship in terms of survival between Child-Pugh stage, the extent of hepatic resection and the presence of clinical PH. National Center for Biotechnology InformationU.

No-mortality liver resection for hepatocellular carcinoma in cirrhotic and noncirrhotic motoal Results of an observational study in patients. Portal hypertension PH is related to increase in intrahepatic resistance due to the structural subversion of the cirrhotic seeie and loss of vascular bed, and bleeding from gastro-esophageal varices is one of the most important complications of cirrhosis.

On motol contrary, other authors did not detect a significant correlation between PH and liver failure after surgery[ 3233 ]. Surgical treatment is the most effective treatment for HCC and the mortality after surgery has decreased in recent years in relation to improved surgical techniques and peri-operative management of patients. Also, in patients with PH, limited liver resection can be performed with results comparable to those in patients without PH. Influence of the extent of hepatectomy on the portal hypertensive state in patients with hepatoma.

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